1. Products Licensed in the US to Treat Hemophilia A
  2. Products Licensed in the US to Treat Hemophilia B
  3. Products Licensed in the US to Treat Von Willebrand Disease
  4. Bypassing Agents (BPA) Licensed in the US to Treat Patients with Inherited Hemophilia A or B and Inhibitors
  5. Non-Factor Replacement Therapies for Hemophilia A with Inhibitors
  6. Products Licensed in the US to Treat Non-congenital Hemophilia Patients with Acquired Hemophilia A
  7. Products Licensed in the US to Treat Rare Bleeding Disorders
  8. Factor Products Licensed in the US for Use in Individuals with Thrombosis Risk
  9. Blood Bank Components Licensed in the US to Treat Rare Bleeding Disorders
  10. Antifibrinolytic Agents

 

Products Licensed in the US to Treat Hemophilia A


Recombinant Factor VIII Products


Recombinant Humanized Bispecific FIXa and FX directed monoclonal antibody for use in patients with inherited hemophilia A


Human Plasma-Derived Immunoaffinity-purified Factor VIII Concentrates


Human Plasma-derived Concentrates that Contain Factor VIII and Von Willebrand Factor


Desmopressin Formulations to Treat Mild Hemophilia A

 

  • DDAVP Injection | Aventis Pharma
  • Stimate Nasal Spray for Bleeding - Currently Unavailable


    Gene Therapy

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Products Licensed in the US to Treat Hemophilia B


Recombinant Factor IX Concentrates


Human Plasma-derived Coagulation Factor IX Concentrates

  • AlphaNine SD (PDF to come)
  • Mononine (PDF to come)

Gene Therapy

 

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Products Licensed in the US to Treat Von Willebrand Disease


Desmopressin Formulations to Treat Type 1 and Type 2 VWD

  • DDAVP Injection | Aventis Pharma
  • Stimate Nasal Spray for Bleeding | CSL Behring - Currently Unavailable

Recombinant Von Willebrand Factor


Human Plasma-derived Concentrates that Contain Factor VIII and Von Willebrand Factor

 

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Bypassing Agents (BPA) Licensed in the US to Treat Patients with Inherited Hemophilia A or B and Inhibitors


Human Plasma-derived Activated Prothrombin Complex Concentrate for Use in Patient with Inherited Hemophilia A or B and Inhibitors to Factor VIII or IX


Recombinant Factor VIIa Concentrate for Use in Patients with Inherited Hemophilia A or B and Inhibitors to Factor VIII or IX

 

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Non-Factor Replacement Therapies Licensed in the US to Treat Patients with Inherited Hemophilia A and Inhibitors


Recombinant Humanized Bispecific FIXa and FX directed monoclonal antibody for Use in Patients with Inherited Hemophilia A and Inhibitors to Factor VIII

 

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Products Licensed in the US to Treat Non-congenital Hemophilia Patients with Acquired Hemophilia A


Recombinant Factor Concentrates for use in patients with Acquired Inhibitors to Factor VIII

 

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Products Licensed in the US to Treat Rare Bleeding Disorders


Human Plasma-derived Concentrate to Treat Afibrinogenemia and Hypofibrinogenemia (Factor 1 deficiency)


Recombinant Factor VIIa Concentrate for Treatment of Factor VII Deficiency


Human Plasma-derived Concentrate to Treat Factor X Deficiency


Human Plasma-Derived Concentrate to Treat Factor XIII Deficiency


Recombinant Factor XIII-A Subunit Deficiency


Human Plasma-derived Prothrombin Complex Concentrates for Use in Patients with Factor II or Factor X Deficiency

  • Bebulin | Shire (Takeda)
  • Profilnine (PDF to come)

 

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Factor Products Licensed in the US for Use in Individuals with Thrombosis Risk


Products to Treat Antithrombin Deficiency


Human Plasma-derived Protein C Concentrate to Treat Protein C Deficiency


Product to Treat Plasminogen Deficiency

 

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Blood Bank Components Licensed in the US to Treat Rare Bleeding Disorders


Fresh Frozen Plasma Products to Treat Patients with Factor V or Factor XI Deficiency


Cryoprecipitate to Treat Patients with Dysfibrinogenemia

  • Cryoprecipitate | Some Community Blood Centers
  • Cryoprecipitate, pooled | Some Community Blood Centers

 

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Antifibrinolytic Agents


Aminocaproic Acid

  • Aminocaproic Acid
  • Amicar (oral) Xanodyne
  • Amicar (tablet) Xanodyne
  • Amicar (IV) American Regent Hospira

Tranexamic Acid

  • Cyklokapron Pfizer
  • Lysteda Xanodyne

 

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